Rejuran® (Topical PDRN) in Newton, MA

Rejuran® (Topical PDRN)

What Is Rejuran®?

Skin repair is something the body already knows how to do. Rejuran® simply gives it better materials to work with.

Rejuran® is a topical treatment containing PDRN, or polydeoxyribonucleotide, a compound derived from salmon DNA that has been used in wound care and tissue repair for decades. At Longevity Lab & Aesthetics, we offer Rejuran® as part of our regenerative approach because it works at a level most topical products never reach. Rather than sitting on the surface of the skin, PDRN treatment is absorbed and interacts with the cells responsible for repair and renewal, helping the skin rebuild its own structure from the inside out.

Rejuran® can be used on its own as a calming, restorative step or applied immediately after microneedling to enhance absorption and support the healing process.

Treatment Areas

Rejuran® is applied topically, often in combination with other treatments that create temporary channels in the skin to improve absorption.

Full Face

Overall skin quality improvements, including texture, tone, hydration, and firmness, are the most common results from full-face Rejuran® treatment. It is particularly well-suited for skin that feels dull, unsettled, or is recovering from a recent procedure.

Under-Eye Area

Thin, delicate skin under the eyes responds particularly well to the repair-focused properties of PDRN. Rejuran® helps calm and hydrate this area without the need for anything more aggressive.

Neck and Décolletage

Skin in these areas often shows signs of aging earlier than the face. Rejuran® helps restore quality and resilience to skin that has started to thin or become uneven.

Hands

The backs of the hands benefit from the hydrating and regenerative effects of PDRN, particularly when the skin has become crepey or uneven in texture.

Benefits of Rejuran®

Rejuran® stands apart from most topical treatments because its active ingredient is not just moisturizing or temporarily plumping the skin. It is actively supporting the repair process at a cellular level.

Supports tissue repair.

PDRN supports the activity of cells involved in skin repair and collagen production.

Soothes sensitive skin.

Rejuran® is gentle on reactive or delicate skin and works well for people who cannot tolerate more aggressive treatments.

Improves skin from within.

Rather than coating the surface, Rejuran® works with the skin’s own biology to improve how it functions.

Deeply hydrating.

PDRN improves the skin’s ability to retain moisture, contributing to a healthier, more supple appearance over time.

Works well after procedures.

Applied after microneedling or other treatments that temporarily open the skin, Rejuran® absorbs more deeply and produces a more meaningful response.

No downtime.

Rejuran® can be applied post-procedure or as a standalone step with no recovery required.

Is This Right for You?

Rejuran® is a good fit for people who want to support skin health at a foundational level without an aggressive approach. You may be a good fit if:

You have had a recent microneedling, laser, or peel treatment and want to support recovery

You are noticing changes in skin texture, hydration, or overall quality

You have sensitive skin and want a gentle but effective regenerative option

You prefer gentle, science-based skin care that works with your body's natural repair process

You are in good general health and not pregnant or nursing

What To Expect

Rejuran® is typically applied during or immediately after a treatment that creates temporary micro-channels in the skin, such as microneedling. This allows the PDRN to penetrate more deeply and work more effectively than it would on intact skin alone. It can also be applied on its own as a calming, hydrating treatment.

After application, Rejuran® is gently massaged into the skin to support full absorption. Most people notice improvements in skin hydration and texture within the first few weeks. Greater improvements in skin quality and resilience build over one to two months with regular sessions.

Before Your Appointment

Come with clean skin. Avoid retinoids and exfoliating products for one to two days before your appointment. If Rejuran® is being combined with another treatment, your provider will give you specific preparation instructions. Avoid excess sun exposure or tanning beforehand.

After Your Appointment

Wait a few hours before washing your face. Keep the skin calm and hydrated for the first 24 to 48 hours. Avoid active skincare ingredients like retinoids and acids for two to three days. Protect the skin from direct sun exposure and apply SPF once the skin has settled.

Frequently Asked Questions

What is PDRN, and how does it help the skin?

PDRN stands for polydeoxyribonucleotide. It is a naturally derived compound from salmon DNA that has been used in medical wound care for many years. In skin care, it supports the cells responsible for tissue repair and collagen production, making it particularly helpful for skin that is irritated, sensitive, or recovering from a procedure.

Is Rejuran® the same as a filler or injectable?

No. Rejuran® is a topical treatment that is applied to the surface of the skin and absorbed rather than injected beneath it. It does not add volume or change the structure of the face.

Does it work on its own, or does it need to be combined with something?

Rejuran® can be used on its own, but it works best when applied after a treatment that temporarily opens the skin, like microneedling. This allows it to penetrate more deeply and produce a more meaningful response.

How soon will I see results?

Most people notice improved hydration and a calmer complexion within a few days. Greater improvements in skin quality build gradually over one to two months.

Is it suitable for sensitive skin?

Yes. Rejuran® is generally well-tolerated even by people with sensitive or reactive skin. Its gentle, repair-focused approach makes it a good option for those who cannot use more aggressive treatments.

Do you offer virtual consultations?

Yes. We are licensed in both Massachusetts and Florida and offer telehealth consultations for anyone who prefers to connect remotely before coming in.

TAKE THE FIRST STEP

Healthy, confident skin starts with the right aesthetic approach. Our team creates personalized treatment plans focused on long-term skin health and natural results, helping you feel confident inside and out for years to come. Schedule your consultation to begin your longevity-focused aesthetic journey.

617-413-6899

Schedule A Consultation

Let’s connect

It can be challenging to start something new, but we are here to assist you. Feel free to contact us if you would like to learn more about a service, discuss treatment options, or get to know us better.

No pressure, no pushy sales, just kind, thoughtful guidance from a team that genuinely cares.